Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 29930Generated: October 26, 2026

2-Thiophenecarbonyl chloride → 5-Methoxy-2-(thiophene-2-carbonyl)benzoic acid

https://huagongshe.com/reaction/29930

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiophenecarbonyl chlorideHCID 78928—
Reactant2-Bromo-5-methoxybenzoic acidHCID 89906—
Product5-Methoxy-2-(thiophene-2-carbonyl)benzoic acidHCID 69212983—

Reaction Steps

This compound is obtained according to the procedure described in 1.1. by reacting thiophene-2-carboxylic acid chloride and 2-bromo-5-methoxybenzoic acid after halogen-lithium exchange. It is used in crude form in the following reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423030B2
Source datasetuspto-grants-2008_09
ORD IDord-bf6e0b3446874b6d93e4631883a57601
Source noteuspto-grants-2008_09