4-Amino-1-(2-naphthyl)methylpiperidine → 4-(3,4-dimethoxyphenyl)-7-methoxy-N-[1-(naphthalen-2-ylmethyl)piperidin-4-yl]phthalazin-1-amine

HRID 29949Notes

Reaction equation

HRID 29949 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH3:13])[CH:10]=2)[C:5]([C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[C:16]([O:22][CH3:23])[CH:15]=2)=[N:4][N:3]=1.[NH2:24][CH:25]1[CH2:30][CH2:29][N:28]([CH2:31][C:32]2[CH:41]=[CH:40][C:39]3[C:34](=[CH:35][CH:36]=[CH:37][CH:38]=3)[CH:33]=2)[CH2:27][CH2:26]1>>[CH3:23][O:22][C:16]1[CH:15]=[C:14]([C:5]2[C:6]3[C:11](=[CH:10][C:9]([O:12][CH3:13])=[CH:8][CH:7]=3)[C:2]([NH:24][CH:25]3[CH2:26][CH2:27][N:28]([CH2:31][C:32]4[CH:41]=[CH:40][C:39]5[C:34](=[CH:35][CH:36]=[CH:37][CH:38]=5)[CH:33]=4)[CH2:29][CH2:30]3)=[N:3][N:4]=2)[CH:19]=[CH:18][C:17]=1[O:20][CH3:21]

Participants

3

Reactant 2

HCID 111958234-Amino-1-(2-naphthyl)methylpiperidineHCID 866122141-Chloro-4-(3,4-dimethoxyphenyl)-7-methoxyphthalazine

Product 1

HCID 692114584-(3,4-dimethoxyphenyl)-7-methoxy-N-[1-(naphthalen-2-ylmethyl)piperidin-4-yl]phthalazin-1-amine

Procedure

This compound is obtained according to the procedure described in 1.4. by reacting 1-chloro-4-(3,4-dimethoxyphenyl)-7-methoxyphthalazine with 4-amino-1-(naphthalen-2-ylmethyl)piperidine.

Workup

  1. customThis compound is obtained

Sources & evidence

ORD record
ord-e8ea9ddbe69441ddadd288268c23b5f1
Source dataset
uspto-grants-2008_09
Patent number
US07423030B2

Reaction notes

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