HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 5,7-Dimethoxyphthalazin-1(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 2-Formyl-3,5-dimethoxybenzoic acid | HCID 15369428 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5,7-Dimethoxyphthalazin-1(2H)-one | HCID 21138693 | 86% |
Reaction Steps
The 2-formyl-3,5-dimethoxybenzoic acid (2.7 g, 13 mmol) is partially dissolved in 300 mL of ethanol, and 6.2 mL of hydrazine hydrate are then added. The mixture is refluxed for 6 hours. After cooling, the precipitate formed is filtered off and then dried. 2.3 g of a white solid are obtained (86% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423030B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-ffc2fbeaf2ac4c7e8cb57124306c181b |
| Source note | uspto-grants-2008_09 |