4-Amino-1-(2-naphthyl)methylpiperidine → 5,7-dimethoxy-N-[1-(naphthalen-2-ylmethyl)piperidin-4-yl]phthalazin-1-amine

HRID 29954Notes

Reaction equation

HRID 29954 reaction equation
Cl[C:2]1[C:11]2[C:6](=[C:7]([O:14][CH3:15])[CH:8]=[C:9]([O:12][CH3:13])[CH:10]=2)[CH:5]=[N:4][N:3]=1.[NH2:16][CH:17]1[CH2:22][CH2:21][N:20]([CH2:23][C:24]2[CH:33]=[CH:32][C:31]3[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=3)[CH:25]=2)[CH2:19][CH2:18]1>>[CH3:15][O:14][C:7]1[CH:8]=[C:9]([O:12][CH3:13])[CH:10]=[C:11]2[C:6]=1[CH:5]=[N:4][N:3]=[C:2]2[NH:16][CH:17]1[CH2:18][CH2:19][N:20]([CH2:23][C:24]2[CH:33]=[CH:32][C:31]3[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=3)[CH:25]=2)[CH2:21][CH2:22]1

Participants

3

Reactant 2

HCID 111958234-Amino-1-(2-naphthyl)methylpiperidineHCID 866122151-Chloro-5,7-dimethoxyphthalazine

Product 1

HCID 692144985,7-dimethoxy-N-[1-(naphthalen-2-ylmethyl)piperidin-4-yl]phthalazin-1-amine

Procedure

This compound is obtained according to the procedure described in 2.4 by reacting 1-chloro-5,7-dimethoxyphthalazine described in 13.2 with 4-amino-1-(naphthalen-2-ylmethyl)piperidine.

Workup

  1. customThis compound is obtained

Sources & evidence

ORD record
ord-ecc7c4a3c82846679b8753d74a6bdf5a
Source dataset
uspto-grants-2008_09
Patent number
US07423030B2

Reaction notes

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