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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 29966Generated: October 25, 2026

Phenylacetyl chloride → 3,5-Dimethoxy-2-(phenylacetyl)benzoic acid

https://huagongshe.com/reaction/29966

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylacetyl chlorideHCID 7679—
ReactantMethyl 3,5-DimethoxybenzoateHCID 75074—
Product3,5-Dimethoxy-2-(phenylacetyl)benzoic acidHCID 69213889—

Reaction Steps

This compound is synthesized by reacting methyl 3,5-dimethoxybenzoate with phenylacetyl chloride via the Friedel-Crafts reaction, followed by saponification of the ester obtained, according to the method described in 2.1. It is used in crude form in the following reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423030B2
Source datasetuspto-grants-2008_09
ORD IDord-f474b4227e984e3b8f420708e210bfb8
Source noteuspto-grants-2008_09