4-Amino-1-(2-naphthyl)methylpiperidine → 4-benzyl-5,7-dimethoxy-N-[1-(naphthalen-2-ylmethyl)piperidin-4-yl]phthalazin-1-amine

HRID 29969Notes

Reaction equation

HRID 29969 reaction equation
[CH2:1]([C:8]1[C:17]2[C:12](=[CH:13][C:14]([O:20][CH3:21])=[CH:15][C:16]=2[O:18][CH3:19])[C:11](Cl)=[N:10][N:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:23][CH:24]1[CH2:29][CH2:28][N:27]([CH2:30][C:31]2[CH:40]=[CH:39][C:38]3[C:33](=[CH:34][CH:35]=[CH:36][CH:37]=3)[CH:32]=2)[CH2:26][CH2:25]1>>[CH2:1]([C:8]1[C:17]2[C:12](=[CH:13][C:14]([O:20][CH3:21])=[CH:15][C:16]=2[O:18][CH3:19])[C:11]([NH:23][CH:24]2[CH2:25][CH2:26][N:27]([CH2:30][C:31]3[CH:40]=[CH:39][C:38]4[C:33](=[CH:34][CH:35]=[CH:36][CH:37]=4)[CH:32]=3)[CH2:28][CH2:29]2)=[N:10][N:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 111958234-Amino-1-(2-naphthyl)methylpiperidineHCID 86612218HCID 86612218, compound

Product 1

HCID 692138224-benzyl-5,7-dimethoxy-N-[1-(naphthalen-2-ylmethyl)piperidin-4-yl]phthalazin-1-amine

Procedure

This compound is obtained according to the procedure described in 1.4. by reacting 4-benzyl-1-chloro-5,7-dimethoxyphthalazine with 4-amino-1-(naphthalen-2-ylmethyl)piperidine.

Workup

  1. customThis compound is obtained

Sources & evidence

ORD record
ord-e6a69c69bd3e47e5b781b7b5ca176c83
Source dataset
uspto-grants-2008_09
Patent number
US07423030B2

Reaction notes

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