Pyridine → N-[4-[(5,6-Dihydro-7H-pyrimido[5,4-d][1]benzazepin-7-yl)carbonyl]phenyl]-2,4-dichlorobenzamide

HRID 299695Notes

Reaction equation

HRID 299695 reaction equation
[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[cH:8][cH:9][c:10]([C:11](=[O:12])[Cl:13])[cH:14][cH:15]2)[cH:16][cH:17][c:18]([Cl:20])[cH:19]1.[cH:36]1[cH:37][cH:38][n:39][cH:40][cH:41]1.[n:21]1[cH:22][n:23][cH:24][c:25]2[c:31]1-[c:30]1[c:29]([cH:35][cH:34][cH:33][cH:32]1)[NH:28][CH2:27][CH2:26]2>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[cH:8][cH:9][c:10]([C:11](=[O:12])[N:28]3[CH2:27][CH2:26][c:25]4[cH:24][n:23][cH:22][n:21][c:31]4-[c:30]4[c:29]3[cH:35][cH:34][cH:33][cH:32]4)[cH:14][cH:15]2)[cH:16][cH:17][c:18]([Cl:20])[cH:19]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 116023454-[(2,4-dichlorobenzoyl)amino]benzoyl ChlorideHCID 543969886,7-dihydro-5H-benzo[b]pyrimido[4,5-d]azepine

Product 1

HCID 67623798N-[4-[(5,6-Dihydro-7H-pyrimido[5,4-d][1]benzazepin-7-yl)carbonyl]phenyl]-2,4-dichlorobenzamide

Sources & evidence

ORD record
ord-c5aedac6f8a04c6cadfc3800a1f33108
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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