2-Fluorotoluene → 2-Chloro-4-[1-(3-fluoro-4-methyl-phenyl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridine

HRID 299708Notes

Reaction equation

HRID 299708 reaction equation
[BH:16]([OH:17])[OH:18].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([C:8]#[C:9][c:10]2[n:11][c:12]([CH3:15])[nH:13][cH:14]2)[cH:7]1.[F:19][c:20]1[cH:21][cH:22][cH:23][cH:24][c:25]1[CH3:26]>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([C:8]#[C:9][c:10]2[n:11][c:12]([CH3:15])[n:13](-[c:22]3[cH:21][c:20]([F:19])[c:25]([CH3:26])[cH:24][cH:23]3)[cH:14]2)[cH:7]1

Participants

4

Reactant 3

HCID 72412-FluorotolueneHCID 61668Boronic AcidHCID 178418879HCID 178418879, compound

Product 1

HCID 865953152-Chloro-4-[1-(3-fluoro-4-methyl-phenyl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridine

Sources & evidence

ORD record
ord-3f785525a6a34c18936afe553a9948d9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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