(+-)-2-Butanol → 1-(2-Fluoro-4-(3-((7-methoxy-1,5-naphthyridin-4-ylamino)methyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)pyrrolidin-2-one
Reaction equation
[CH3:38][CH2:39][CH:40]([OH:41])[CH3:42].[Cl:25][c:26]1[cH:27][cH:28][n:29][c:30]2[cH:31][c:32]([O:36][CH3:37])[cH:33][n:34][c:35]12.[NH2:1][CH2:2][c:3]1[n:4][n:5][c:6]2[n:7]1[n:8][c:9](-[c:12]1[cH:13][c:14]([F:24])[c:15]([N:18]3[C:19](=[O:23])[CH2:20][CH2:21][CH2:22]3)[cH:16][cH:17]1)[cH:10][cH:11]2>>[NH:1]([CH2:2][c:3]1[n:4][n:5][c:6]2[n:7]1[n:8][c:9](-[c:12]1[cH:13][c:14]([F:24])[c:15]([N:18]3[C:19](=[O:23])[CH2:20][CH2:21][CH2:22]3)[cH:16][cH:17]1)[cH:10][cH:11]2)[c:26]1[cH:27][cH:28][n:29][c:30]2[cH:31][c:32]([O:36][CH3:37])[cH:33][n:34][c:35]12Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-a03760790a2f4536839dfd72098c283e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…