HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-5-methoxybenzoic acid → 2-Cyclopropanecarbonyl-5-methoxybenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-5-methoxybenzoic acid | HCID 89906 | — |
| Reactant | N-Methoxy-N-methylcyclopropanecarboxamide | HCID 15643267 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Solvent | Diisopropyl Ether | HCID 7914 | — |
| Product | 2-Cyclopropanecarbonyl-5-methoxybenzoic acid | HCID 69212937 | — |
Reaction Steps
This compound is synthesized according to the method described in 3.2. by reacting 2-bromo-5-methoxybenzoic acid pretreated with n-butyllithium with cyclopropyl-N-methoxy-N-methylcarboxamide. A yellow powder is obtained by precipitation in isopropyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423030B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-3bc13d99e0224c2db27405ca1fc340a0 |
| Source note | uspto-grants-2008_09 |