4-Amino-1-(2-naphthyl)methylpiperidine → 4-Cyclopropyl-7-methoxy-N-(1-(naphthalen-2-ylmethyl)piperidin-4-yl]phthalazin-1-amine

HRID 29981Notes

Reaction equation

HRID 29981 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH3:13])[CH:10]=2)[C:5]([CH:14]2[CH2:16][CH2:15]2)=[N:4][N:3]=1.[NH2:17][CH:18]1[CH2:23][CH2:22][N:21]([CH2:24][C:25]2[CH:34]=[CH:33][C:32]3[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=3)[CH:26]=2)[CH2:20][CH2:19]1>>[CH:14]1([C:5]2[C:6]3[C:11](=[CH:10][C:9]([O:12][CH3:13])=[CH:8][CH:7]=3)[C:2]([NH:17][CH:18]3[CH2:19][CH2:20][N:21]([CH2:24][C:25]4[CH:34]=[CH:33][C:32]5[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=5)[CH:26]=4)[CH2:22][CH2:23]3)=[N:3][N:4]=2)[CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 111958234-Amino-1-(2-naphthyl)methylpiperidineHCID 866122201-Chloro-4-cyclopropyl-7-methoxyphthalazine

Product 1

HCID 692132734-Cyclopropyl-7-methoxy-N-(1-(naphthalen-2-ylmethyl)piperidin-4-yl]phthalazin-1-amine

Procedure

This compound is obtained according to the procedure described in 1.4. by reacting 1-chloro-4-cyclopropyl-7-methoxyphthalazine with 4-amino-1-(naphthalen-2-ylmethyl)piperidine.

Workup

  1. customThis compound is obtained

Sources & evidence

ORD record
ord-a1f89d14b645480bbfee77d5b1fc2c03
Source dataset
uspto-grants-2008_09
Patent number
US07423030B2

Reaction notes

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