4-Amino-1-(2-naphthyl)methylpiperidine → HCID 69209397, compound

HRID 29985Notes

Reaction equation

HRID 29985 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]3[C:19]4[C:14](=[CH:15][C:16]([O:20][CH3:21])=[CH:17][CH:18]=4)[C:13]([Cl:22])=[N:12][N:11]=3)=[CH:9][C:4]=2[O:3][CH2:2]1.[NH2:23][CH:24]1[CH2:29][CH2:28][N:27]([CH2:30][C:31]2[CH:40]=[CH:39][C:38]3[C:33](=[CH:34][CH:35]=[CH:36][CH:37]=3)[CH:32]=2)[CH2:26][CH2:25]1>>[ClH:22].[ClH:22].[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]3[C:19]4[C:14](=[CH:15][C:16]([O:20][CH3:21])=[CH:17][CH:18]=4)[C:13]([NH:23][CH:24]4[CH2:25][CH2:26][N:27]([CH2:30][C:31]5[CH:40]=[CH:39][C:38]6[C:33](=[CH:34][CH:35]=[CH:36][CH:37]=6)[CH:32]=5)[CH2:28][CH2:29]4)=[N:12][N:11]=3)=[CH:9][C:4]=2[O:3][CH2:2]1

Participants

3

Reactant 2

HCID 111958234-Amino-1-(2-naphthyl)methylpiperidineHCID 866122214-(1,3-Benzodioxol-5-yl)-1-chloro-7-methoxyphthalazine

Product 1

HCID 69209397HCID 69209397, compound

Procedure

This compound is obtained according to the procedure described in 1.4. by reacting 4-(1,3-benzodioxol-5-yl)-1-chloro-7-methoxyphthalazine with 4-amino-1-(naphthalen-2-ylmethyl)piperidine. By treatment with a solution of hydrogen chloride in diethyl ether, a precipitate forms, which is filtered off, washed with diethyl ether and dried under reduced pressure. The hydrochloride obtained is in the form of a white solid.

Workup

  1. customThis compound is obtained
  2. filtrationBy treatment with a solution of hydrogen chloride in diethyl ether, a precipitate forms, which is filtered off
  3. washwashed with diethyl ether
  4. customdried under reduced pressure

Sources & evidence

ORD record
ord-7204c825ab3946d4976f56aededdc9d4
Source dataset
uspto-grants-2008_09
Patent number
US07423030B2

Reaction notes

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