Acetic Acid → N-(3-bromo-5-methylphenyl)-4-(difluoromethyl)pyrimidin-2-amine
Reaction equation
[Br:11][c:12]1[cH:13][c:14]([NH2:15])[cH:16][c:17]([CH3:19])[cH:18]1.[C:20]([OH:21])(=[O:22])[CH3:23].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([CH:8]([F:9])[F:10])[n:7]1.[Cl:30][CH2:31][Cl:32].[O:24]1[CH2:25][CH2:26][O:27][CH2:28][CH2:29]1>>[c:2]1([NH:15][c:14]2[cH:13][c:12]([Br:11])[cH:18][c:17]([CH3:19])[cH:16]2)[n:3][cH:4][cH:5][c:6]([CH:8]([F:9])[F:10])[n:7]1Participants
6
Sources & evidence
- ORD record
- ord-51052de563224ae08ff2b8df07cdb4dd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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