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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 299995Generated: October 30, 2026

2-Chloropyrimidine → 6-(2-Chloro-5-fluoro-4-pyrimidinyl)-4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazole

https://huagongshe.com/reaction/299995

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChloropyrimidineHCID 74404—
ReactantN-{5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]pyrimidin-2-amineHCID 46220502—
Product6-(2-Chloro-5-fluoro-4-pyrimidinyl)-4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazoleHCID 78358206—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-93f4ffb3df894f07b14aaa697479c9e2
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)