4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole → 4-(4-Chloro-phenyl)-1-methyl-4-[4-(1H-pyrazol-4-yl)-phenyl]-piperidine

HRID 300027Notes

Reaction equation

HRID 300027 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([c:15]3[cH:16][cH:17][c:18]([Cl:21])[cH:19][cH:20]3)[CH2:9][CH2:10][N:11]([CH3:14])[CH2:12][CH2:13]2)[cH:6][cH:7]1.[CH3:22][C:23]1([CH3:24])[C:25]([CH3:26])([CH3:27])[O:28][B:29]([c:30]2[cH:31][n:32][nH:33][cH:34]2)[O:35]1>>[c:2]1(-[c:30]2[cH:31][n:32][nH:33][cH:34]2)[cH:3][cH:4][c:5]([C:8]2([c:15]3[cH:16][cH:17][c:18]([Cl:21])[cH:19][cH:20]3)[CH2:9][CH2:10][N:11]([CH3:14])[CH2:12][CH2:13]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 27740104-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 576913994-(4-Bromophenyl)-4-(4-chlorophenyl)-1-methylpiperidine

Product 1

HCID 113825744-(4-Chloro-phenyl)-1-methyl-4-[4-(1H-pyrazol-4-yl)-phenyl]-piperidine

Sources & evidence

ORD record
ord-e11c74aea8bf4002909cf0ab7bdc72b7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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