4-Amino-1-(2-naphthyl)methylpiperidine → 4-butyl-7-methoxy-N-[1-(naphthalen-2-ylmethyl)piperidin-4-yl]phthalazin-1-amine

HRID 30003Notes

Reaction equation

HRID 30003 reaction equation
[CH2:1]([C:5]1[C:14]2[C:9](=[CH:10][C:11]([O:15][CH3:16])=[CH:12][CH:13]=2)[C:8](Cl)=[N:7][N:6]=1)[CH2:2][CH2:3][CH3:4].[NH2:18][CH:19]1[CH2:24][CH2:23][N:22]([CH2:25][C:26]2[CH:35]=[CH:34][C:33]3[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=3)[CH:27]=2)[CH2:21][CH2:20]1>>[CH2:1]([C:5]1[C:14]2[C:9](=[CH:10][C:11]([O:15][CH3:16])=[CH:12][CH:13]=2)[C:8]([NH:18][CH:19]2[CH2:20][CH2:21][N:22]([CH2:25][C:26]3[CH:35]=[CH:34][C:33]4[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=4)[CH:27]=3)[CH2:23][CH2:24]2)=[N:7][N:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 111958234-Amino-1-(2-naphthyl)methylpiperidineHCID 866122254-Butyl-1-chloro-7-methoxyphthalazine

Product 1

HCID 692114874-butyl-7-methoxy-N-[1-(naphthalen-2-ylmethyl)piperidin-4-yl]phthalazin-1-amine

Procedure

This compound is obtained according to the procedure described in 1.4. by reacting 4-butyl-1-chloro-7-methoxyphthalazine with 4-amino-1-(naphthalen-2-ylmethyl)piperidine.

Workup

  1. customThis compound is obtained

Sources & evidence

ORD record
ord-03dd8346fcb64e5eb5e3b133b496f56b
Source dataset
uspto-grants-2008_09
Patent number
US07423030B2

Reaction notes

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