4-(2,4-Difluorobenzyl)piperidine → 2-[4-(2,4-Difluoro-benzyl)-piperidin-1-yl]-2-oxo-N-(2-oxo-2,3-dihydro-benzoxazol-6-yl)-acetamide
Reaction equation
[F:1][c:2]1[c:3]([CH2:4][CH:5]2[CH2:6][CH2:7][NH:8][CH2:9][CH2:10]2)[cH:11][cH:12][c:13]([F:15])[cH:14]1.[O:16]=[c:17]1[o:18][c:19]2[c:20]([nH:21]1)[cH:22][cH:23][c:24]([NH:26][C:27]([C:28](=[O:29])[OH:30])=[O:31])[cH:25]2>>[F:1][c:2]1[c:3]([CH2:4][CH:5]2[CH2:6][CH2:7][N:8]([C:28]([C:27]([NH:26][c:24]3[cH:23][cH:22][c:20]4[c:19]([o:18][c:17](=[O:16])[nH:21]4)[cH:25]3)=[O:31])=[O:29])[CH2:9][CH2:10]2)[cH:11][cH:12][c:13]([F:15])[cH:14]1Participants
3
Sources & evidence
- ORD record
- ord-117f9919caf14bdb9b65cfb6db90c790
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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