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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 30016Generated: October 25, 2026

2-Bromo-5-methoxybenzoic acid → 2-Acetyl-5-methoxybenzoic acid

https://huagongshe.com/reaction/30016

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-5-methoxybenzoic acidHCID 89906—
ReactantN-Methoxy-N-methylacetamideHCID 537505—
ReactantButyllithiumHCID 178418339—
Product2-Acetyl-5-methoxybenzoic acidHCID 20163283—

Reaction Steps

This compound is synthesized according to the method described in 3.2. by reacting 2-bromo-5-methoxybenzoic acid pretreated with n-butyllithium with N-methoxy-N-methylacetamide. It is used in crude form in the following reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423030B2
Source datasetuspto-grants-2008_09
ORD IDord-919f3b533e4a42edb8eb1acaf06fb298
Source noteuspto-grants-2008_09