4-Amino-1-(2-naphthyl)methylpiperidine → HCID 69208996, compound
Reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH3:13])[CH:10]=2)[C:5]([CH3:14])=[N:4][N:3]=1.[NH2:15][CH:16]1[CH2:21][CH2:20][N:19]([CH2:22][C:23]2[CH:32]=[CH:31][C:30]3[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=3)[CH:24]=2)[CH2:18][CH2:17]1>>[CH3:13][O:12][C:9]1[CH:10]=[C:11]2[C:6]([C:5]([CH3:14])=[N:4][N:3]=[C:2]2[NH:15][CH:16]2[CH2:17][CH2:18][N:19]([CH2:22][C:23]3[CH:32]=[CH:31][C:30]4[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=4)[CH:24]=3)[CH2:20][CH2:21]2)=[CH:7][CH:8]=1Participants
3
Procedure
This compound is obtained according to the procedure described in 1.4. by reacting 1-chloro-7-methoxy-4-methylphthalazine with 4-amino-1-(naphthalen-2-yl-methyl)piperidine.
Workup
- customThis compound is obtained
Sources & evidence
- ORD record
- ord-6c5a20f275444514bad69ab2a9823a2a
- Source dataset
- uspto-grants-2008_09
- Patent number
- US07423030B2
Reaction notes
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