4-Amino-1-(2-naphthyl)methylpiperidine → HCID 69213870, compound
Reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([F:12])[CH:10]=2)[C:5]([C:13]2[CH:18]=[CH:17][C:16]([F:19])=[CH:15][CH:14]=2)=[N:4][N:3]=1.[NH2:20][CH:21]1[CH2:26][CH2:25][N:24]([CH2:27][C:28]2[CH:37]=[CH:36][C:35]3[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=3)[CH:29]=2)[CH2:23][CH2:22]1>>[F:12][C:9]1[CH:10]=[C:11]2[C:6]([C:5]([C:13]3[CH:18]=[CH:17][C:16]([F:19])=[CH:15][CH:14]=3)=[N:4][N:3]=[C:2]2[NH:20][CH:21]2[CH2:22][CH2:23][N:24]([CH2:27][C:28]3[CH:37]=[CH:36][C:35]4[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=4)[CH:29]=3)[CH2:25][CH2:26]2)=[CH:7][CH:8]=1Participants
3
Procedure
This compound is obtained according to the procedure described in 1.4. by reacting 1-chloro-7-fluoro-4-(4-fluorophenyl)phthalazine with 4-amino-1-(naphthalen-2-ylmethyl)piperidine.
Workup
- customThis compound is obtained
Sources & evidence
- ORD record
- ord-a1b7e6f3e5c944f7a49192b3b6994c36
- Source dataset
- uspto-grants-2008_09
- Patent number
- US07423030B2
Reaction notes
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