HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-5-methoxybenzoic acid → 5-Methoxy-2-pyridin-3-ylbenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-5-methoxybenzoic acid | HCID 89906 | — |
| Reactant | N-Methoxy-N-methylnicotinamide | HCID 10558996 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | 5-Methoxy-2-pyridin-3-ylbenzoic acid | HCID 46315937 | — |
Reaction Steps
This compound is synthesized according to the method described in 3.2. by reacting 2-bromo-5-methoxybenzoic acid pretreated with n-butyllithium with N-methoxy-N-methylnicotinamide. After precipitation in aqueous phase at pH 4, followed by filtration and drying, a beige-coloured powder is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423030B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-3ea30621b6904a65840e6a85fe72c5cc |
| Source note | uspto-grants-2008_09 |