2-Bromo-5-methoxybenzoic acid → 2-(3,4-Dimethylbenzoyl)-5-methoxybenzoic acid

HRID 30038Notes

Reaction equation

HRID 30038 reaction equation
Br[C:2]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].C([Li])CCC.[CH3:18][C:19]1[CH:20]=[C:21]([CH:28]=[CH:29][C:30]=1[CH3:31])[C:22](N(OC)C)=[O:23]>>[CH3:18][C:19]1[CH:20]=[C:21]([CH:28]=[CH:29][C:30]=1[CH3:31])[C:22]([C:2]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5])=[O:23]

Participants

4

Reactant 3

HCID 899062-Bromo-5-methoxybenzoic acidHCID 14973055N-Methoxy-N,3,4-trimethylbenzamideHCID 178418339Butyllithium

Product 1

HCID 692132722-(3,4-Dimethylbenzoyl)-5-methoxybenzoic acid

Procedure

This compound is synthesized according to the method described in 3.2. by reacting 2-bromo-5-methoxybenzoic acid pretreated with n-butyllithium with 3,4-dimethyl-N-methoxy-N-methylbenzamide.

Workup

  1. customThis compound is synthesized

Sources & evidence

ORD record
ord-c0ead3b4eaad40669a841cef9368df91
Source dataset
uspto-grants-2008_09
Patent number
US07423030B2

Reaction notes

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