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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 300401Generated: October 30, 2026

Tetrahydrofuran → Tert-butyl 4-(8-chloro-1,5-naphthyridin-3-yl)-4-hydroxypiperidine-1-carboxylate

https://huagongshe.com/reaction/300401

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
Reactant3-Bromo-8-chloro-1,5-naphthyridineHCID 13459137—
ReactantButyllithiumHCID 178418339—
ProductTert-butyl 4-(8-chloro-1,5-naphthyridin-3-yl)-4-hydroxypiperidine-1-carboxylateHCID 57691287—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-4bf366f55e7c494a99bad54eb9ed9ecb
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)