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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 30041Generated: October 29, 2026

N-Methoxy-N-methyl-2-phenoxyacetamide → 5-Methoxy-2-(2-phenoxyacetyl)benzoic acid

https://huagongshe.com/reaction/30041

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methoxy-N-methyl-2-phenoxyacetamideHCID 56163—
Reactant2-Bromo-5-methoxybenzoic acidHCID 89906—
ReactantButyllithiumHCID 178418339—
Product5-Methoxy-2-(2-phenoxyacetyl)benzoic acidHCID 69213260—

Reaction Steps

This compound is synthesized according to the method described in 3.2. by reacting 2-bromo-5-methoxybenzoic acid pretreated with n-butyllithium with N-methoxy-N-methyl-2-phenoxyacetamide. The product is used in crude form in the following reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423030B2
Source datasetuspto-grants-2008_09
ORD IDord-0c09127364164e61aa507a002626d335
Source noteuspto-grants-2008_09