Bicarbonate Ion → 6-[4-chloro-3-(4-fluoro-phenyl)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-pyrazine-2-carboxylic acid dimethylamide
Reaction equation
[C:47](=[O:48])([OH:49])[O-:50].[CH3:35][N:36]([C:37](=[O:38])[c:39]1[n:40][c:41]([Cl:45])[cH:42][n:43][cH:44]1)[CH3:46].[CH3:52][C:53]#[N:54].[CH3:55][c:56]1[cH:57][cH:58][cH:59][cH:60][cH:61]1.[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][c:7]1[B:8]1[O:9][C:10]([CH3:11])([CH3:12])[C:13]([CH3:14])([CH3:15])[O:16]1)[n:17]([CH2:27][O:28][CH2:29][CH2:30][Si:31]([CH3:32])([CH3:33])[CH3:34])[cH:18][c:19]2-[c:20]1[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]1.[Na+:51]>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][c:7]1-[c:41]1[n:40][c:39]([C:37]([N:36]([CH3:35])[CH3:46])=[O:38])[cH:44][n:43][cH:42]1)[n:17]([CH2:27][O:28][CH2:29][CH2:30][Si:31]([CH3:32])([CH3:33])[CH3:34])[cH:18][c:19]2-[c:20]1[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-bba1ee478bf44243b7652e79d0732bd1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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