Toluene → racemic (2'S,3R)-6-chloro-2'-(3-chlorophenyl)-4'-isopropyl-6'-thioxospiro[3H-indole-3,3'-piperidine]-2(1H)-one
Reaction equation
[CH3:28][O:29][c:30]1[cH:31][cH:32][c:33]([P:34]2(=[S:35])[S:36][P:38](=[S:39])([c:40]3[cH:41][cH:42][c:43]([O:44][CH3:45])[cH:46][cH:47]3)[S:37]2)[cH:48][cH:49]1.[CH3:50][c:51]1[cH:52][cH:53][cH:54][cH:55][cH:56]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]21[CH:12]([c:21]2[cH:22][c:23]([Cl:27])[cH:24][cH:25][cH:26]2)[NH:13][C:14](=[O:20])[CH2:15][CH:16]1[CH:17]([CH3:18])[CH3:19]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]21[CH:12]([c:21]2[cH:22][c:23]([Cl:27])[cH:24][cH:25][cH:26]2)[NH:13][C:14](=[S:37])[CH2:15][CH:16]1[CH:17]([CH3:18])[CH3:19]Participants
4
Sources & evidence
- ORD record
- ord-e429871cf3184288b8016e0339df47c9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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