4-Amino-1-(2-naphthyl)methylpiperidine → 7-Methoxy-N-[1-(naphthalen-2-ylmethyl)piperidin-4-yl]-5-phenylphthalazin-1-amine dihydrochloride

HRID 30057Notes

Reaction equation

HRID 30057 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH:8]=[C:9]([O:12][CH3:13])[CH:10]=2)[CH:5]=[N:4][N:3]=1.[NH2:20][CH:21]1[CH2:26][CH2:25][N:24]([CH2:27][C:28]2[CH:37]=[CH:36][C:35]3[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=3)[CH:29]=2)[CH2:23][CH2:22]1>>[ClH:1].[ClH:1].[CH3:13][O:12][C:9]1[CH:10]=[C:11]2[C:6]([CH:5]=[N:4][N:3]=[C:2]2[NH:20][CH:21]2[CH2:22][CH2:23][N:24]([CH2:27][C:28]3[CH:37]=[CH:36][C:35]4[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=4)[CH:29]=3)[CH2:25][CH2:26]2)=[C:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:8]=1

Participants

3

Reactant 2

HCID 111958234-Amino-1-(2-naphthyl)methylpiperidineHCID 877354141-Chloro-7-methoxy-5-phenylphthalazine

Product 1

HCID 692094577-Methoxy-N-[1-(naphthalen-2-ylmethyl)piperidin-4-yl]-5-phenylphthalazin-1-amine dihydrochloride

Procedure

This compound is obtained according to the procedure described in 2.4. by reacting 1-chloro-7-methoxy-5-phenylphthalazine with 4-amino-1-(naphthalen-2-yl-methyl)piperidine.

Workup

  1. customThis compound is obtained

Sources & evidence

ORD record
ord-3855d74ff2f7423281692fc2bc0cff90
Source dataset
uspto-grants-2008_09
Patent number
US07423030B2

Reaction notes

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