2-Bromo-5-methoxybenzoic acid → HCID 69212695, compound

HRID 30058Notes

Reaction equation

HRID 30058 reaction equation
Br[C:2]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].C([Li])CCC.[CH2:18]([O:25][CH2:26][C:27](N(OC)C)=[O:28])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH2:18]([O:25][CH2:26][C:27]([C:2]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5])=[O:28])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

4

Reactant 3

HCID 899062-Bromo-5-methoxybenzoic acidHCID 114584642-(Benzyloxy)-N-methoxy-N-methylacetamideHCID 178418339Butyllithium

Product 1

HCID 69212695HCID 69212695, compound

Procedure

This compound is synthesized according to the method described in 3.2. by reacting 2-bromo-5-methoxybenzoic acid pretreated with n-butyllithium with 2-benzyloxy-N-methoxy-N-methylacetamide. The product is used in crude form in the following reaction.

Workup

  1. customThis compound is synthesized
  2. customin the following reaction

Sources & evidence

ORD record
ord-036e2ad68ef74ff1a12901fee284cd6c
Source dataset
uspto-grants-2008_09
Patent number
US07423030B2

Reaction notes

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