1-Pyrrolidineethanamine → 8-Cyclohexyl-5-oxo-2-(2-pyrrolidin-1-yl-ethylamino)-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester

HRID 300744Notes

Reaction equation

HRID 300744 reaction equation
[CH2:9]([CH3:10])[O:11][C:12](=[O:13])[c:14]1[c:15](=[O:34])[c:16]2[c:17]([n:18][c:19]([S:22]([CH3:23])(=[O:24])=[O:25])[n:20][cH:21]2)[n:26]([CH:28]2[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]2)[cH:27]1.[N:1]1([CH2:6][CH2:7][NH2:8])[CH2:2][CH2:3][CH2:4][CH2:5]1>>[N:1]1([CH2:6][CH2:7][NH:8][c:19]2[n:18][c:17]3[c:16]([c:15](=[O:34])[c:14]([C:12]([O:11][CH2:9][CH3:10])=[O:13])[cH:27][n:26]3[CH:28]3[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]3)[cH:21][n:20]2)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 13441-PyrrolidineethanamineHCID 252234828-Cyclohexyl-2-methanesulfonyl-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester

Product 1

HCID 685835138-Cyclohexyl-5-oxo-2-(2-pyrrolidin-1-yl-ethylamino)-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-3471dff93afd47b0a00708d7c70a8c16
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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