Fluorophenylacetic acid → 4-(4-Bromophenylsulphonyl)-1-(2-fluoro-2-phenylethyl)piperidine
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[CH:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)[cH:6][cH:7]1.[F:17][CH:18]([C:19]([OH:20])=[O:21])[c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[CH:11]2[CH2:12][CH2:13][N:14]([CH2:19][CH:18]([F:17])[c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[CH2:15][CH2:16]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-d04df05e8036493fb52c16459b4f9609
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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