HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 300832Generated: October 25, 2026
Dimethyl Sulfoxide → 6-chloro-5-[2,6-difluoro-4-[3-(methylamino)propoxy]phenyl]-2-pyrazin-2-yl-N-(1,1,1-trifluoropropan-2-yl)pyrimidin-4-amine
https://huagongshe.com/reaction/300832
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | Sodium ion | HCID 923 | — |
| Reactant | Hydride | HCID 166653 | — |
| Reactant | 3-(Methylamino)-1-propanol | HCID 10148986 | — |
| Reactant | 6-chloro-2-pyrazin-2-yl-5-(2,4,6-trifluorophenyl)-N-(1,1,1-trifluoropropan-2-yl)pyrimidin-4-amine | HCID 11293429 | — |
| Product | 6-chloro-5-[2,6-difluoro-4-[3-(methylamino)propoxy]phenyl]-2-pyrazin-2-yl-N-(1,1,1-trifluoropropan-2-yl)pyrimidin-4-amine | HCID 11260601 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
|---|
| ORD ID | ord-1abd3418954c401e9ee819ba101d7082 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
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