2-(4-Fluorophenyl)-3-hydroxy-3-pyridin-4-yl-propionic acid methyl ester → 2-(4-Fluorophenyl)-3-(2-methylsulfanyl-pyrimidin-4-yl)-3-oxo-propionic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3]([CH:4]([CH:5]([c:6]1[n:7][c:8]([S:12][CH3:13])[n:9][cH:10][cH:11]1)[OH:14])[c:15]1[cH:16][cH:17][c:18]([F:21])[cH:19][cH:20]1)=[O:22].[CH3:23][O:24][C:25](=[O:26])[CH:27]([c:28]1[cH:29][cH:30][c:31]([F:32])[cH:33][cH:34]1)[CH:35]([OH:36])[c:37]1[cH:38][cH:39][n:40][cH:41][cH:42]1>>[CH3:1][O:2][C:3]([CH:4]([C:5]([c:6]1[n:7][c:8]([S:12][CH3:13])[n:9][cH:10][cH:11]1)=[O:14])[c:15]1[cH:16][cH:17][c:18]([F:21])[cH:19][cH:20]1)=[O:22]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-b3d78991a1664de0a1ec010253b593c6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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