HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-amino-1-piperidinecarboxylate → 4-[6-Amino-5-(2-fluoro-benzoyl)-pyridin-2-ylamino]-piperidine-1-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-amino-1-piperidinecarboxylate | HCID 100867 | — |
| Reactant | (2-Amino-6-chloro-pyridin-3-yl)-(2-fluoro-phenyl)-methanone | HCID 58590830 | — |
| Product | 4-[6-Amino-5-(2-fluoro-benzoyl)-pyridin-2-ylamino]-piperidine-1-carboxylic acid ethyl ester | HCID 11661022 | — |
Reaction Steps
The title compound was prepared from (2-Amino-6-chloro-pyridin-3-yl)-(2-fluoro-phenyl)-methanone (Example 7) and ethyl-4-amino-1-piperidine carboxylate (Aldrich) using the procedure described in Step B. Example 6. HRMS, observed: 386.1762, calcd for M+: 386.1754.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423051B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-0b0a6e779a6f49c4ab9303d399238a7b |
| Source note | uspto-grants-2008_09 |