化工社化工社 化学情報印刷レポート · 研究参考用
Propionyl chloride → 1-{4-[6-Amino-5-(2-fluoro-benzoyl)-pyridin-2-ylamino]-piperidin-1-yl}-propan-1-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Propionyl chloride | HCID 62324 | — |
| 反応物 | [2-Amino-6-(piperidin-4-ylamino)-pyridin-3-yl]-(2-fluoro-phenyl)-methanone | HCID 58590835 | — |
| 生成物 | 1-{4-[6-Amino-5-(2-fluoro-benzoyl)-pyridin-2-ylamino]-piperidin-1-yl}-propan-1-one | HCID 11653588 | — |
反応手順
The title compound was prepared from [2-Amino-6-(piperidin-4-ylamino)-pyridin-3-yl]-(2-fluoro-phenyl)-methanone (Example 9) and propionyl chloride (Aldrich 98%) using the procedure described in Example 12. HRMS, observed: 370.1807, Calcd for M+: 370.1805.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07423051B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-15409d617f494192978b52004eeb6668 |
| 出典メモ | uspto-grants-2008_09 |