Pyridine → 1,1-Dimethylethyl {1-[5-(2-chloro-4-pyrimidinyl)-4-(3-{[(2,6-difluorophenyl)sulfonyl]amino}-2-fluorophenyl)-1,3-thiazol-2-yl]-1-methylethyl}carbamate
Reaction equation
[F:32][c:33]1[c:34]([S:40](=[O:41])(=[O:42])[Cl:43])[c:35]([F:39])[cH:36][cH:37][cH:38]1.[NH2:1][c:2]1[c:3]([F:31])[c:4](-[c:8]2[n:9][c:10]([C:20]([CH3:21])([CH3:22])[NH:23][C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[s:11][c:12]2-[c:13]2[n:14][c:15]([Cl:19])[n:16][cH:17][cH:18]2)[cH:5][cH:6][cH:7]1.[cH:44]1[cH:45][cH:46][n:47][cH:48][cH:49]1>>[NH:1]([c:2]1[c:3]([F:31])[c:4](-[c:8]2[n:9][c:10]([C:20]([CH3:21])([CH3:22])[NH:23][C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[s:11][c:12]2-[c:13]2[n:14][c:15]([Cl:19])[n:16][cH:17][cH:18]2)[cH:5][cH:6][cH:7]1)[S:40]([c:34]1[c:33]([F:32])[cH:38][cH:37][cH:36][c:35]1[F:39])(=[O:41])=[O:42]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-e79dce58a1c6475c932da51e1683decc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…