HuagongsheHuagongshe Chemistry Print Report · For research reference only
[1-(Methylsulfonyl)piperidin-4-yl]amine trifluoroacetate → [2-Amino-6-(1-methanesulfonyl-piperidin-4-ylamino)-pyridin-3-yl]-(3-methoxy-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [1-(Methylsulfonyl)piperidin-4-yl]amine trifluoroacetate | HCID 11975076 | — |
| Reactant | (2-Amino-6-chloro-pyridin-3-yl)-(3-methoxy-phenyl)-methanone | HCID 58590838 | — |
| Product | [2-Amino-6-(1-methanesulfonyl-piperidin-4-ylamino)-pyridin-3-yl]-(3-methoxy-phenyl)-methanone | HCID 11647097 | — |
Reaction Steps
The title compound was prepared from (2-Amino-6-chloro-pyridin-3-yl)-(3-methoxy-phenyl)-methanone (Example 17) and 1-methanesulfonyl-piperidin-4-ylamine (Step A, Example 6) using the procedure described in Step B. Example 6. HRMS, 405.1595 observed:, Calcd for (M+H)+: 405.1591.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423051B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-51e78b8a7b1f46b5814e59ee7446e481 |
| Source note | uspto-grants-2008_09 |