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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 30117Generated: October 26, 2026

2-Bromo-4-fluoroanisole → (2-Amino-6-chloro-pyridin-3-yl)-(5-fluoro-2-methoxy-phenyl)-methanone

https://huagongshe.com/reaction/30117

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-4-fluoroanisoleHCID 136292—
Reactant2-Amino-6-chloro-N-methoxy-N-methyl-nicotinamideHCID 58590824—
Product(2-Amino-6-chloro-pyridin-3-yl)-(5-fluoro-2-methoxy-phenyl)-methanoneHCID 58590829—

Reaction Steps

The title compound was prepared from 2-Amino-6-chloro-N-methoxy-N-methyl-nicotinamide (Example 3) and 2-bromo-4-fluoroanisole (Aldrich) using the procedure described in Example 7. HRMS, observed: 280.0417, Calcd for M+: 280.0415.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423051B2
Source datasetuspto-grants-2008_09
ORD IDord-139c7582a2184a3e8bb025b5d221774a
Source noteuspto-grants-2008_09