Methyl 2-bromopropionate → 2-[3-(2,4-dichlorobenzyl)-8-fluoro-4-methyl-2-oxo-1,2-dihydroquinolin-5-yloxy]propionic Acid Methyl Ester

HRID 301174Notes

Reaction equation

HRID 301174 reaction equation
[CH3:24][O:25][C:26]([CH:27]([CH3:28])[Br:29])=[O:30].[Cl:1][c:2]1[c:3]([CH2:4][c:5]2[c:6](=[O:18])[nH:7][c:8]3[c:9]([F:17])[cH:10][cH:11][c:12]([OH:16])[c:13]3[c:14]2[CH3:15])[cH:19][cH:20][c:21]([Cl:23])[cH:22]1>>[Cl:1][c:2]1[c:3]([CH2:4][c:5]2[c:6](=[O:18])[nH:7][c:8]3[c:9]([F:17])[cH:10][cH:11][c:12]([O:16][CH:27]([C:26]([O:25][CH3:24])=[O:30])[CH3:28])[c:13]3[c:14]2[CH3:15])[cH:19][cH:20][c:21]([Cl:23])[cH:22]1

Participants

3

Reactant 2

HCID 95576Methyl 2-bromopropionateHCID 687858183-(2,4-dichlorobenzyl)-8-fluoro-5-hydroxy-4-methyl-1H-quinolin-2-one

Product 1

HCID 687801012-[3-(2,4-dichlorobenzyl)-8-fluoro-4-methyl-2-oxo-1,2-dihydroquinolin-5-yloxy]propionic Acid Methyl Ester

Sources & evidence

ORD record
ord-3fdc090aca7b47719843677a3a5eadcb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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