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HRID30123

反应详情

EQUATION

反应方程式

HRID 30123 的结构方程式

REACTANTS

反应物

2
结构：CC(C)S(=O)(=O)Cl
HCID82408

Isopropyl sulfonyl chloride

C3H7ClO2S

结构：COc1ccc(F)cc1C(=O)c1cnc(NC2CCNCC2)nc1N.O=C(O)C(F)(F)F
HCID21070627

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(F)cc1C(=O)c1ccc(NC2CCN(S(=O)(=O)C(C)C)CC2)nc1N
HCID11561482

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from [4-amino-2-(piperidin-4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone trifluoroacetic acid salt (Example 22) and isopropyl sulfonyl chloride (Aldrich 97%) using the procedure described in Example 24. HRMS, observed: 451.1814, Calcd for (M+H)+: 451.1810.