HRID30125

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7998

Propyl chloroformate

C4H7ClO2

结构：COc1ccc(F)cc1C(=O)c1cnc(NC2CCNCC2)nc1N.O=C(O)C(F)(F)F

HCID21070627

未命名化合物

PRODUCTS

生成物

结构：CCCOC(=O)N1CCC(Nc2ccc(C(=O)c3cc(F)ccc3OC)c(N)n2)CC1

HCID11711671

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from [4-amino-2-(piperidin4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone trifluoroacetic acid salt (Example 22) and 1-propyl chloroformate (Aldrich 98%) using the procedure described in Example 24. HRMS, observed: 431.2095, Calcd for (M+H)+: 431.2089.