1-Benzyl-4-piperidylamine → [2-Amino-6-(1-benzyl-piperidin-4-ylamino)-pyridin-3-yl]-(5-fluoro-2-methoxy-phenyl)-methanone

Participants

Role	Name	HCID	Charge
Reactant	1-Benzyl-4-piperidylamine	HCID 415852	—
Reactant	(2-Amino-6-chloro-pyridin-3-yl)-(5-fluoro-2-methoxy-phenyl)-methanone	HCID 58590829	—
Product	[2-Amino-6-(1-benzyl-piperidin-4-ylamino)-pyridin-3-yl]-(5-fluoro-2-methoxy-phenyl)-methanone	HCID 11704736	—

Reaction Steps

The title compound was prepared from (2-amino-6-chloropyridin-3-yl)-(5-fluoro-2-methoxyphenyl)methanone (Example 19) and 4-amino-1-benzylpiperidine (Ardrich) using the procedure described in Step B. Example 6. HRMS, observed: 435.2196, Calcd for (M+H)+: 435.2191.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07423051B2
Source dataset	uspto-grants-2008_09
ORD ID	ord-e92a58b2d5ae4f7783e882274bab8338
Source note	uspto-grants-2008_09