HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Iodoanisole → (2-Amino-6-chloro-pyridin-3-yl)-(4-methoxy-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Iodoanisole | HCID 69676 | — |
| Reactant | 2-Amino-6-chloro-N-methoxy-N-methyl-nicotinamide | HCID 58590824 | — |
| Reactant | HCID 178506735 | HCID 178506735 | — |
| Product | (2-Amino-6-chloro-pyridin-3-yl)-(4-methoxy-phenyl)-methanone | HCID 58590836 | — |
Reaction Steps
The title compound was prepared from 2-Amino-6-chloro-N-methoxy-N-methyl-nicotinamide (Example 3) and 4-methoxyphenyllithium freshly prepared from 4-iodoanisole (Aldrich) using the procedure described in Example 7. HRMS, observed: 262.0512, Calcd for M+: 262.0509.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423051B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-176c6c62ac88485a97538c505ba1b9d6 |
| Source note | uspto-grants-2008_09 |