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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 30134Generated: October 25, 2026

4-Fluoroiodobenzene → (2-Amino-6-chloro-pyridin-3-yl)-(4-fluoro-phenyl)-methanone

https://huagongshe.com/reaction/30134

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluoroiodobenzeneHCID 9605—
Reactant2-Amino-6-chloro-N-methoxy-N-methyl-nicotinamideHCID 58590824—
Product(2-Amino-6-chloro-pyridin-3-yl)-(4-fluoro-phenyl)-methanoneHCID 58590828—

Reaction Steps

The title compound was prepared from 2-Amino-6-chloro-N-methoxy-N-methyl-nicotinamide (Example 3) and 1-fluoro-4-iodobenzene (Aldrich 99%) using the procedure described in Example 7. HRMS, observed: 250.0314, Calcd for M+: 250.0309.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423051B2
Source datasetuspto-grants-2008_09
ORD IDord-63e9c089843b45879c1458c9f2b44eb9
Source noteuspto-grants-2008_09