5-Chloro-2-(4-fluorophenoxy)nicotinic acid → tert-butyl 4-[1-[[5-chloro-2-(4-fluorophenoxy)pyridine-3-carbonyl]amino]ethyl]benzoate
Reaction equation
[Cl:1][c:2]1[cH:3][n:4][c:5]([O:11][c:12]2[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]2)[c:6]([C:7](=[O:8])[OH:9])[cH:10]1.[NH2:19][CH:20]([CH3:21])[c:22]1[cH:23][cH:24][c:25]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[cH:33][cH:34]1>>[Cl:1][c:2]1[cH:3][n:4][c:5]([O:11][c:12]2[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]2)[c:6]([C:7](=[O:9])[NH:19][CH:20]([CH3:21])[c:22]2[cH:23][cH:24][c:25]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[cH:33][cH:34]2)[cH:10]1Participants
3
Sources & evidence
- ORD record
- ord-257486c356ba41749937f21398d6726e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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