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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 30142생성일: 2026년 10월 25일

[1-(Methylsulfonyl)piperidin-4-yl]amine trifluoroacetate → [2-Amino-6-(1-methanesulfonyl-piperidin-4-ylamino)-pyridin-3-yl]-(5-fluoro-2-methoxy-4-methyl-phenyl)-methanone

https://huagongshe.com/reaction/30142

반응식

참여 물질

역할이름HCID투입량
반응물[1-(Methylsulfonyl)piperidin-4-yl]amine trifluoroacetateHCID 11975076—
반응물(2-Amino-6-chloro-pyridin-3-yl)-(5-fluoro-2-methoxy-4-methyl-phenyl)-methanoneHCID 58590831—
생성물[2-Amino-6-(1-methanesulfonyl-piperidin-4-ylamino)-pyridin-3-yl]-(5-fluoro-2-methoxy-4-methyl-phenyl)-methanoneHCID 11669262—

반응 단계

The title compound was prepared from (2-Amino-6-chloro-pyridin-3-yl)-(5-fluoro-2-methoxy-4-methyl-phenyl)-methanone (Example 43) and 1-methanesulfonyl-piperidin-4-ylamine (Step A, Example 6) using the procedure described in Step B. Example 6. HRMS, observed 437.1653, Calcd for (M+H)+: 437.1654.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07423051B2
출처 데이터셋uspto-grants-2008_09
ORD IDord-563ca61d07894ce6b1c970640de235b0
출처 메모uspto-grants-2008_09