1-(Phenylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-pyrrolo[2,3-B]pyridine-2-carboxaldehyde → N-(4-{4-[2-formyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1-ethyl-1H-pyrazol-3-yl}phenyl)-N'-phenylurea

HRID 301500Notes

Reaction equation

HRID 301500 reaction equation
[Br:1][c:2]1[c:3](-[c:9]2[cH:10][cH:11][c:12]([NH:15][C:16](=[O:17])[NH:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[cH:13][cH:14]2)[n:4][n:5]([CH2:7][CH3:8])[cH:6]1.[c:25]1([S:31](=[O:32])(=[O:33])[n:34]2[c:35]([CH:52]=[O:53])[cH:36][c:37]3[c:38]2[n:39][cH:40][cH:41][c:42]3[B:43]2[O:44][C:45]([CH3:46])([CH3:47])[C:48]([CH3:49])([CH3:50])[O:51]2)[cH:26][cH:27][cH:28][cH:29][cH:30]1>>[c:2]1(-[c:42]2[c:37]3[cH:36][c:35]([CH:52]=[O:53])[n:34]([S:31]([c:25]4[cH:26][cH:27][cH:28][cH:29][cH:30]4)(=[O:32])=[O:33])[c:38]3[n:39][cH:40][cH:41]2)[c:3](-[c:9]2[cH:10][cH:11][c:12]([NH:15][C:16](=[O:17])[NH:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[cH:13][cH:14]2)[n:4][n:5]([CH2:7][CH3:8])[cH:6]1

Participants

3

Reactant 2

HCID 462368991-(Phenylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-pyrrolo[2,3-B]pyridine-2-carboxaldehydeHCID 68997560N-[4-(4-Bromo-1-ethyl-1H-pyrazol-3-yl)phenyl]-N′-phenylurea

Product 1

HCID 46236618N-(4-{4-[2-formyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1-ethyl-1H-pyrazol-3-yl}phenyl)-N'-phenylurea

Sources & evidence

ORD record
ord-3318aded495440e7bbd3ad1f231512eb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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