3,5-Difluorobenzyl bromide → 2-[1-(3,5-difluoro-benzyl)-1H-pyrazol-3-yl]-4-methyl-thiazole-5-carboxylic acid (pyridin-3-ylmethyl)amide
Reaction equation
[Br:22][CH2:23][c:24]1[cH:25][c:26]([F:31])[cH:27][c:28]([F:30])[cH:29]1.[n:1]1[cH:2][c:3]([CH2:7][NH:8][C:9](=[O:10])[c:11]2[c:12]([CH3:21])[n:13][c:14](-[c:16]3[nH:17][n:18][cH:19][cH:20]3)[s:15]2)[cH:4][cH:5][cH:6]1>>[n:1]1[cH:2][c:3]([CH2:7][NH:8][C:9](=[O:10])[c:11]2[c:12]([CH3:21])[n:13][c:14](-[c:16]3[n:17][n:18]([CH2:23][c:24]4[cH:25][c:26]([F:31])[cH:27][c:28]([F:30])[cH:29]4)[cH:19][cH:20]3)[s:15]2)[cH:4][cH:5][cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-3f93487aad0347b096d9e0ab7283c977
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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