HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → (RS)-2-[5-(3-Chloro-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-piperidine-1-carboxylic acid tert butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | 1-Boc-2-Piperidineacetic Acid | HCID 5058536 | — |
| Reactant | HCID 178478066 | HCID 178478066 | — |
| Product | (RS)-2-[5-(3-Chloro-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-piperidine-1-carboxylic acid tert butyl ester | HCID 86628998 | 57.8% |
Reaction Steps
The title compound (1.21 g) was prepared from 2-carboxymethyl-piperidine-1-carboxylic acid tert butyl ester (1.35 g), 5-(3-chlorophenyl)tetrazole (1.0 g) and dicyclohexylcarbodiimide (1.15 g) according to the method of description 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423052B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-b49f5489381a4ce58c4ac9870981c75f |
| Source note | uspto-grants-2008_09 |