7-amino-4-{4-[ethyl(methyl)amino]cyclohexyl}-2-methyl-2,3-dihydro-1H-isoindol-1-one → Diethyl[4-({4-[(7-{4-[ethyl(methyl)amino]cyclohexyl}-2-methyl-3-oxo-2,3-dihydro-1H-isoindol-4-yl)amino]-5-(trifluoromethyl)pyrimidin-2-yl}amino)-3-methoxybenzyl]phosphonate
Reaction equation
[CH2:1]([CH3:2])[O:3][P:4]([O:5][CH2:6][CH3:7])(=[O:8])[CH2:9][c:10]1[cH:11][c:12]([O:28][CH3:29])[c:13]([NH:16][c:17]2[n:18][cH:19][c:20]([C:24]([F:25])([F:26])[F:27])[c:21]([Cl:23])[n:22]2)[cH:14][cH:15]1.[NH2:30][c:31]1[cH:32][cH:33][c:34]([CH:42]2[CH2:43][CH2:44][CH:45]([N:48]([CH3:49])[CH2:50][CH3:51])[CH2:46][CH2:47]2)[c:35]2[c:39]1[C:38](=[O:40])[N:37]([CH3:41])[CH2:36]2>>[CH2:1]([CH3:2])[O:3][P:4]([O:5][CH2:6][CH3:7])(=[O:8])[CH2:9][c:10]1[cH:11][c:12]([O:28][CH3:29])[c:13]([NH:16][c:17]2[n:18][cH:19][c:20]([C:24]([F:25])([F:26])[F:27])[c:21]([NH:30][c:31]3[cH:32][cH:33][c:34]([CH:42]4[CH2:43][CH2:44][CH:45]([N:48]([CH3:49])[CH2:50][CH3:51])[CH2:46][CH2:47]4)[c:35]4[c:39]3[C:38](=[O:40])[N:37]([CH3:41])[CH2:36]4)[n:22]2)[cH:14][cH:15]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-85a70f08becc4f79836d4bcc63f30fcf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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