HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-1-(4-fluorophenyl)ethanone → (RS)-2-{[2-(4-Fluoro-phenyl)-2-oxo-ethylcarbamoyl]-methyl}-piperidine-1-carboxylic acid tert butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-1-(4-fluorophenyl)ethanone | HCID 1581177 | — |
| Reactant | 1-Boc-2-Piperidineacetic Acid | HCID 5058536 | — |
| Product | (RS)-2-{[2-(4-Fluoro-phenyl)-2-oxo-ethylcarbamoyl]-methyl}-piperidine-1-carboxylic acid tert butyl ester | HCID 86629006 | 61.9% |
Reaction Steps
The title compound (0.77 g) was prepared from 2-carboxymethyl-piperidine-1-carboxylic acid tert butyl ester (0.80 g) and 2-amino-1-(4-fluoro-phenyl)-ethanone (0.63 g) according to the method of description 20.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423052B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-f27181ed3be844dead513c3355c44c1e |
| Source note | uspto-grants-2008_09 |